Businesses beginning with O
- Oak Haven Lodge, Inc.
- Oakey's Funeral Service & Crematory
- Oberlin Appraisal Service, Inc.
- Oberlin Realty Company
- Old Dominion Services of Roanoke, Inc.
- Old Dutch Supermarkets
- Old Virginia Hand Hewn Log Homes, Inc.
- One Stop Gutter Shop, Inc.
- Orkin Pest Control
- Oscar W. Smith Mechanical Contractor, Inc.
- Ostrom Electrical Contracting, Inc.
- Outdoor Lighting Perspectives of Southern VA
- Outdoor Power Equipment
- OxygenPlus Medical Systems, Inc.
